Bloodstone Blend Capsules

$30.00$55.00


REVITALIZATION | FOCUS

Bloodstone calms the mind, dispels confusion, and enhances the decision-making process. It can revitalize the mind if you are mentally exhausted.


Crystal Clear’s Bloodstone Blend is an energizer and body tonic. Adrafinil, ashwagandha extract, ginseng extract, phenylpiracetam, and DMAE work together to focus and stimulate the brain as well as purify the body. If you are looking for a well rounded energy blend with healing herbal properties, try Bloodstone.


This product has not been approved the FDA. This product is not intended to treat, cure, or prevent any disease.


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Description


WHAT IS ADRAFINIL?

Adrafinil is a behavioral stimulant with the potential to increase cognition. Adrafinil is a prodrug to modafinil, meaning it converts to modafinil in the body. Adrafinil can promote wakefulness, relieve fatigue, increase alertness, and improve attention abilities. It takes about 45-60 minutes to feel the full effects of adrafinil, and the effects can last up to 12 hours. Adrafinil is often used by people who work long hours or need to stay up for extended periods of time.


ASHWAGANDHA BENEFITS

Ashwagandha has been used in Ayurvedic medicine for thousands of years for treatment of stress, nervous exhaustion, memory loss, insomnia, and for enhanced cognitive processing. Our current demanding societal structure and environmental stressors leave many people with neurological conditions including memory loss, diabetes, brain tumors, and insomnia. Medical studies recommend ashwagandha as a supplement to prevent cognitive decline and maintain healthy brain function. Ashwagandha leaves have a wide variety of effects including anticancer properties, reversal of Alzheimer and Parkinson’s pathologies, memory enhancement, stress and anxiety reduction, antibacterial properties, anti-diabetic, weight loss for adults under chronic stress, antioxidant, cardio-protective, and neuroprotective properties.


WHY PANAX GINSENG?

Highly regarded for its focusing and energizing effects, panax ginseng is the super-tonic root used in Traditional Chinese Medicine for thousands of years. Medical experiments suggest scientific evidence for ginseng’s ability to decrease stress, improve body stamina, enhance memory, and increase mental performance. Crystal Clear Supplements brings you a panax ginseng extract that carries the regarded properties of the medicinal root including increased physical and mental work capacity, anti-fatigue, and anti-stress. The list of health benefits attributed to ginseng is extensive. Other effects associated with panax ginseng include: liver repair, increased wound-healing response, decrease in inflammation, anti-oxidative, and decrease in effects of erectile dysfunction.


PHENYLPIRACETAM

Phenylpiracetam is a nootropic known for its ability to improve cognition, boost locomotor activity, and act as an antidepressant. In medical research, phenylpiracetam showed enhanced memory effects, antidepressant effects, and an increase in locomotor activity with a single administration. Phenylpiracetam is part of the racetam group, a group of drugs with effects such as memory enhancement and neuroprotection. Phenylpiracetam is estimated to be 50 to 60 times more potent than the original racetam, piracetam. In studies on rats, phenylpiracetam reduced anxiety and fear in response to stress and increased exploratory behavior. With its abilities to increase physical endurance and cold resistance, phenylpiracetam is sometimes referred to as an non-specified stimulant.


DMAE & THE BRAIN

DMAE is the precursor to choline, an important neurotransmitter that helps production of acetylcholine which is largely responsible for memory and learning processes in the brain. Medical reports say DMAE has anti-aging properties and can be classified as an antioxidant. Increases in vigilance and attention are also apparent in patients taking DMAE. In a study done on emotionally disturbed patients, DMAE shows an ability to change brain patterns so that the person feels a stronger sense of overall wellbeing, especially after taking DMAE over a period of time (3 months in this study).


RESOURCES


ADRAFINIL

1. Siwak CT, Callahan H, Milgram NW. Adrafinil: effects on behavior and cognition in aged canines. 2000.

2. Rambert FA, Pessonnier J, de Sereville JE, Poiteau AM, Duteil J. A unique psychopharmacologic profile of adrafinil in mice. 1986.

3. Rao RN, Shinde DD, Talluri MV, Agawane SB. LC-ESI-MS determination and pharmacokinetics of adrafinil in rats. 2008.

4. Chariot J, Appia F, Vaille C, Rozé C. Effect of modafinil on pancreatic exocrine secretion in rats. A comparison with adrafinil and related drugs. 1987.


ASHWAGANDHA

1. Choudhary D, Bhattacharyya S, Joshi K. Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled Trial. 2016.

2. Manchanda S, Mishra R, Singh R, Kaur T, Kaur G. Aqueous Leaf Extract of Withania somnifera as a Potential Neuroprotective Agent in Sleep-deprived Rats: a Mechanistic Study. 2016.

3. Ponnusam Y, Louis T, Madhavachandran V, Kumar S, Thoprani N, Hamblin MR, Lakshmanan S. Antioxidant Activity of The Ancient Herb, Holy Basil in CCI4-Induced Liver Injury in Rats. 2015.

4. Samadi AK. Potential Anticancer Properties and Mechanisms of Action of Withanolides. 2015.

5. Candelario M, Cuellar E, Reyes-Ruiz JM, Darabedian N, Feimang Z, Miledi R, Russo-Neustadt A, Limon A. Direct evidence for GABAergic activity of Withania somnifera on mammalian ionotropic GABAA and GABAp receptors. 2015.

6. Mohanty R, Das SK, Singh NR, Patri M. Withania somnifera Leaf Exract Amerliorates Benzo[a]pyrene-Induced Behavioral and Neuromorphological Alterations by Improving Brain Antioxidant Status in Zebrafish (Danio rerio). 2016.

7. Akhoon BA, Pandey S, Tiwari S, Pandey R. Withanolide A offers neuroprotection, ameliorates stress resistance, and prolongs the life expectancy of Caenorhabditis elegans. 2016.

8. Parihar P, Shetty R, Ghafourifar P, Parihar MS. Increase in oxidative stress and mitochondrial impairment in hypothalamus of streptozotocin treated diabetic rat: Antioxidative effect of WIthania somnifera. 2016.

9. Wadhwa R, Konar A, Kaul SC. Nootropic potential of Ashwagandha leaves: Beyond traditional root extracts. 2016.

10. Dar NJ, Hamid A, Ahmad M. Pharmacologic overview of Withania somnifera, the Indian Ginseng. 2015.

11. Durg S, Dhadde SB, Vandal R, Shivakumar BS, Charcan CS. Withania somnifera (Ashwagandha) in neurobehavioral disorders induced by brain oxidative stress in rodents: a systematic review and meta-analysis. 2015.


GINSENG

1. Feng L, Liu XM, Cao FR, Want LS, Chen YX, Pan RL, Liao YH, Wang Q, Chang Q. Anti-stress effects of ginseng total saponins on hindlimb-unloaded rats assessed by a metabolomics study. 2016.

2. Yennurajalingam S, Reddy A, Tannir NM, Chisholm GB, Lee RT, Lopez G, Escalante CP, Manzullo EF, Fresbee Hume S, Williams JL, Cohen L, Bruera E. High-Dose Asian Ginseng (Panax Ginseng) for Cancer-Related Fatigue: A Preliminary Report. 2015.

3. Jiao R, Liu Y, Gao H, Xiao J, So KF. The Anti-Oxiadant and Antitumor Properties of Plant Polysaccharides. 2016.

4. Fulder SJ. Ginseng and the hypothalamic-pituitary control of stress. 1981.

5. Lam P, Cheung F, Tan HY, Wang N, Yuen MF, Feng Y. Hepatoprotective Effects of Chinese Medicinal Herbs: A Focus on Anti-Inflammatory and Anit-Oxidative Activities. 2016.

6. Oliynyk S, Oh S. Actoprotective effect of ginseng: improving mental and physical performance. 2013.

7. Qi B, Liu L, Zhang H, Zhou GX, Wang S, Duan XZ, Bai XY, Wang SM, Zhao DQ. Anti-fatigue effects of proteins isolated from Panax quinquefolium. 2014.

8.Li H, Kang T, Qi B, Kong L, Cao Y, Zhang J, Yang J. Neuroprotective effects of ginseng protein on PI3K/Akt signaling pathways in the hippocampus of D-galactose/AICI3 inducing rats model of Alzheimer’s disease. 2016.

9. Wesnes KA, Ward T, McGinty A, Petrini O. The memory enhancing effects of a Ginkgo biloba/Panax ginseng combination in healthy middle-aged volunteers. 2000.


PHENYLPIRACETAM

1. Samotrueva MA, Tyurenkov IN, Teplyi DL, Serezhnikova TK, Khlebtsova EB. Psychoimmunomodulatory effect of phenotropil in animals with immune stress. 2011.

2.Malykh AG, Sadaie MR. Piracetam and piracetam-like drugs: from basic science to novel clinical application to CNS disorders.

3. Zvejniece L, Svalbe B, Veinberg G, Grinberga S, Vorona M, Kalvinsh I, Dambrova M. Investigation into stereoselective pharmacological activity of phenotropil.

4. Tiurenkov IN, Bagmetov MN, Epishina VV. Comparative evaluation of the neuroprotective activity of phenotropil and piracetam in laboratory animals with experimental cerebral ischemia. 2007.

5. Bobkov IuG, Morozov IS, Glozman OM, Nerobkova LN, Zhmurenko LA. Pharmacological characteristics of a new phenyl analog of piracetam–4-phenylpiracetam. 1983.


DMAE

1. Malanga G, Aguiar MB, Martinex HD, Puntarulo S. New insights on dimethylaminoethanol (DMAE) features as a free radical scavenger. 2012.

2. Dimpfel W, Wedekind W, Keplinger I. Efficacy of dimethylaminoethanol containing vitamin-mineral drug combination on EEG patterns in the presence of different emotional states. 2003.

3. Tadini Ka, Campos PM. In vivo skin effects of a dimethylaminoethanol (DMAE) based formulation. 2009.

4. Blin O, Audebert C, Pitel S, Kaladjian A, Casse-Perrot C, Zaim M, Micallef J, Tisne-Versailles J, Sokoloff P, Chopin P, Marien M. Effects of dimethylaminoethanol pyroglutamate (DMAE p-Glu) against memory deficits induced by scopolamine: evidence from preclinical and clinical studies. 2009.

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